Unbiased Analysis of Today's Healthcare Issues

Are new cancer treatments improving survival or quality of life?

This is the question that a recent study in BMJ by Davis et al. (2017) attempts to answer.  They use data from 48 cancer drugs for 68 indications that were approved by the European Medicines Agency (EMA) between 2009 and 2013.  Among these 68 indications, they found that: only 35 (51%) were associated with significant improvement […]

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The value of surrogate endpoints for predicting real-world survival across five cancer types

You can find one of my recent papers measuring how well survival measures from clinical trials (i.e., overall survival, progression free survival, time to progression) translate into real-world survival outcomes in Current Medical Research and Opinion here.  The abstract is below.   Objective It is unclear how well different outcome measures in randomized controlled trials (RCTs) perform in […]

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